Aldous Huxley (1894–1963) was the author of nearly fifty books and numerous essays, best known for his dystopian novel Brave New World. Humphry Osmond (1917–2004) was a British-trained psychiatrist interested in the biological nature of mental illness and the potential for psychedelic drugs to treat psychoses, especially schizophrenia. In 1953, Huxley sent an appreciative note to Osmond about an article he and a colleague had published on their experiments with mescaline, which inspired an initial meeting and decade-long correspondence. This critical edition provides the complete Huxley-Osmond correspondence, chronicling an exchange between two brilliant thinkers who explored such subjects as psychedelics, the visionary experience, the nature of mind, human potentialities, schizophrenia, death and dying, Indigenous rituals and consciousness, socialism, capitalism, totalitarianism, power and authority, and human evolution. There are references to mutual friends, colleagues, and eminent figures of the day, as well as details about both men's personal lives. The letters bear witness to the development of mind-altering drugs aimed at discovering the mechanisms of mental illness and eventually its treatment. A detailed introduction situates the letters in their historical, social, and literary context, explores how Huxley and Osmond first coined the term "psychedelic," contextualizes their work in mid-century psychiatry, and reflects on their legacy as contributors to the science of mind-altering substances. Psychedelic Prophets is an extraordinary record of a full correspondence between two leading minds and a testament to friendship, intellectualism, empathy, and tolerance. The fact that these sentiments emerge so clearly from the letters, at a historical moment best known for polarizing ideological conflict, threats of nuclear war, and the rise of post-modernism, reveals much about the personalities of the authors and the persistence of these themes today.

Cynthia Bisbee is a psychologist who worked with Humphry Osmond at Bryce Hospital in Alabama for over two decades.

Cynthia Carson Bisbee's profile page

Paul Bisbee worked for the Alabama Department of Mental Health for thirty-five years, first at Bryce Hospital, where he met and worked with Humphry Osmond.

Paul Bisbee's profile page

Erika Dyck is a historian of health, medicine, and Canadian society at the University of Saskatchewan. Her research has concentrated on the history of mental health, institutionalization, and experimentation.
 

Erika Dyck's profile page

Patrick Farrell's profile page

"A deeply nuanced and insightful conversation about psychedelic experience between two first-rate minds, Psychedelic Prophets will delight its readers." Dana Sawyer, Maine College of Art

"This reviewer could not put the volume down once taking the plunge into its richness, it reads almost as an epistolary novel. In chronicling one of the most famous friendships of the twentieth century, it serves as the complete record of a friendship that bridged the cultural divide between science, the medical arts and the literary arts. Huxley and Osmond were one another's guides – to art, to biochemistry, to psychiatry and to love and life." Social History of Medicine

"An enjoyable read, Psychedelic Prophets is a treasure trove of fascinating insights into the life and times of these two extraordinary historical figures and early pioneers of the field of psychedelic study." Charles Grob, Harbor-UCLA Medical Center

"A tour-de-force into the mid-twentieth century Zeitgeist ... a fascinating source for further research into subjects ranging from history, history of psychiatry, literary history, and much more ... read on their own, the letters are a delightful read that bring to light two very remarkable minds of the 20th century." Metascience

"Offering insights into the ideas of two important mid-20th-century thinkers, this volume will appeal to humanities and sciences scholars alike, and the editors' clear explanations make the volume accessible and engaging for nonspecialists. Highly recommended." Choice