Overgrowth Syndromes presents a broad yet in-depth discussion of children who are large at birth or experience excessive postnatal growth or some combination of increased weight, length, and head circumference. Many of these syndromes are associated with an increased frequency of tumors. The book is important because of the ever-increasing number of newly identified overgrowth syndromes and the rapid progression of molecular knowledge of these conditions. It covers: Beckwith Wiedemann syndrome, Simpson-Golabi-Behmel syndrome, Sotos syndrome, Proteus syndrome, Bannayan-Riley-Ruvalcaba syndrome, Klippel-Trenaunay syndrome, neurofibromatosis, and fragile X syndrome, among other topics. Each chapter provides a historical perspective and deals with epidemiology, etiology, and molecular biology when known, clinical and pathological features, diagnostic criteria, and differential diagnosis. The book is encyclopedic in scope. It will be of value to pediatricians, medical geneticists, oncologists, hematologists, surgeons, pathologists, radiologists, dermatologists, nephrologists, and molecular biologists.

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Rosanna Weksberg is at University of Toronto. Giovanni Neri is at Universita Cattolica, Rome.

This is an excellent book for the clinical geneticist or any other clinician who routinely encounters individuals with overgrowth...this book is the first of its kind and is a welcome addition to the field."--Doody's

"Overgrowth Syndromes is unique in that it is comprehensive and yet tightly constructed. It is also wonderfully affordable. The book will be a welcome addition to the reference library of specialists in pediatric pathology, neonatology, other branches of pediatrics, medical genetics, and surgery." -Pediatric and Developmental Pathology, Vol. 6, 2003