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Medical Immunology

Neurocognitive Complications of HIV-Infection

Neuropathogenesis to Implications for Clinical Practice

by (author) Lucette A. Cysique

edited by Sean B. Rourke

Springer Nature
Initial publish date
Oct 2021
Immunology, Neuroscience
  • Hardback

    Publish Date
    Oct 2021
    List Price

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This volume aims at presenting the latest international research and discoveries in the neurocognitive aspects and complications in HIV/AIDS, and how this understanding can shape and inform how we think about clinical practice and patient care in HIV/AIDS as well as lead to a better understanding of the underlying neuropathogenesis.


The chapter, "Metabolic Syndrome and Cardiovascular Disease Impacts on the Pathophysiology and Phenotype of HIV-Associated Neurocognitive Disorders", of this book is available open access under a CC BY 4.0 license at

About the authors

Contributor Notes

Lucette A. Cysique, Ph.D is an Associate Professor and neuropsychologist at the University of New South Wales, Sydney, Australia and a visiting scholar at MAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada. A/Prof. Cysique has been leading cross-disciplinary research into the neurocognitive and brain changes associated with HIV since 2009. A/Prof. Cysique has expertise in the measurement of cognitive trajectories in longitudinal cohort studies and clinical trials, and also contributes to the development of normative neuropsychological data for cross-sectional and longitudinal studies. Additionally, Dr. Cysique has extensive experience in cross-cultural neuropsychology.

Sean B. Rourke, PhD  is a clinical neuropsychologist and international expert in the neurobehavioral complications of HIV/AIDS. He is a scientist with MAP Centre for Urban Health Solutions in the Li Ka Shing Knowledge Institute of St. Michael's Hospital at Unity Health Toronto, a director for REACH Nexus funded by the Canadian Institutes of Health Research, and a professor of psychiatry at the University of Toronto. He is a Fellow with the Canadian and American Psychological Associations, and the Canadian Academy of Health Sciences. As a social entrepreneur his work involves novel approaches to community stakeholder engagement, partnership development across disciplines and sectors, and innovative research-to-action strategies for access to HIV testing and linkages to care ( and ending HIV stigma in Canada (