Mapping Genetic Interactions
- Publisher
- Humana Press
- Initial publish date
- Sep 2021
- Category
- Genetics & Genomics
-
Hardback
- ISBN
- 9781071617397
- Publish Date
- Sep 2021
- List Price
- $321.5
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Description
This volume details methods of identifying synthetic lethal, genetic interactions by various approaches in different model systems including human cancer cells. Chapters guide readers through genetic interactions in model organisms, RNA interference, CRISPR/Cas9 based genome editing technologies, drug-gene interactions, mapping chemical genetic interactions, synergistic drug-gene relations, single cell sequencing, gene expression profiling, and novel genetic interactions. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.
Authoritative and cutting-edge,Genetic Interaction Mappingaims to be a useful practical guide to researches to help further their study in this field.